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Vildagliptin

Vildagliptin
Vildagliptin
Price And Quantity
  • 25
  • Kilograms/Kilograms
  • 25.00 - 50.00 INR
Product Specifications
  • Freezer
  • C17H25N3O2
  • 303.4 g/mol
  • ‎531.3±50.0 °C at 760 mmHg
  • Medicine Grade
  • 98%
  • Pharmaceutical Industry
  • Liquid
    Product Description

    Vildagliptin

    Ball-and-stick model

    Clinical data

    Trade names

    Galvus/Gliptus

    Synonyms

    (2S)-1-{2-[(3-hydroxy-1-adamantyl)amino]acetyl}pyrrolidine-2-carbonitrile

    AHFS/Drugs.com

    International Drug Names

    Routes of
    administration

    Oral

    ATC code

    ·         A10BH02 (WHO)
    A10BD08 (WHO) (with metformin)[1]

    Legal status

    Legal status

    ·         UK: POM (Prescription only)

    Pharmacokinetic data

    Bioavailability

    85%

    Protein binding

    9.3%

    Metabolism

    Mainly hydrolysis to inactive metabolite; CYP450 not appreciably involved

    Biological half-life

    2 to 3 hours

    Excretion

    Renal

    Identifiers

    IUPAC name[show]

    CAS Number

    ·         274901-16-5 

    PubChem CID

    ·         6918537

    IUPHAR/BPS

    ·         6310

    DrugBank

    ·         DB04876 Yes

    ChemSpider

    ·         5293734 Yes

    UNII

    ·         I6B4B2U96P

    KEGG

    ·         D07080 Yes

    ChEMBL

    ·         CHEMBL142703 Yes

    ECHA InfoCard

    100.158.712 Edit this at Wikidata

    Chemical and physical data

    Formula

    C17H25N3O2

    Molar mass

    303.399 g/mol

    3D model (JSmol)

    ·         Interactive image

    Solubility in water

    Freely Soluble in water mg/mL (20 Â°C)

    SMILES

    InChI

    Vildagliptin (previously LAF237, trade names GalvusZomelis,) is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin inhibits the inactivation of GLP-1[2][3] and GIP[3] by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas.

    Vildagliptin has been shown to reduce hyperglycemia in type 2 diabetes mellitus.[2]

    Our packaging materials can retain the products' quality and newness even under extreme shipping and handling conditions. Our packaging provides optimum physical protection. We keep the finished assortment of products in highly developed and spacious space. This helps us in keeping products secure and sorted.

    Trade Information
    • Cash Advance (CA), Cash in Advance (CID)
    • 1000 Per Day
    • 7 Days
    • Middle East, Asia, Africa, Western Europe, Eastern Europe, South America, North America, Central America, Australia
    • GMP,DMF
    Contact Us

    311, Atlantis Heights, Sarabhai Main Road,Vadiwadi, Vadodara, Gujarat, 390007, India
    Phone :2313036