Cookie Img

Vildagliptin

Vildagliptin
Vildagliptin
Product Code : 274901-16-5
1 INR
Price And Quantity
Minimum Order Quantity :
25
Unit of Measure :
Kilograms/Kilograms
Price :
1 INR
Product Description

Vildagliptin

Ball-and-stick model

Clinical data

Trade names

Galvus/Gliptus

Synonyms

(2S)-1-{2-[(3-hydroxy-1-adamantyl)amino]acetyl}pyrrolidine-2-carbonitrile

AHFS/Drugs.com

International Drug Names

Routes of
administration

Oral

ATC code

·         A10BH02 (WHO)
A10BD08 (WHO) (with metformin)[1]

Legal status

Legal status

·         UK: POM (Prescription only)

Pharmacokinetic data

Bioavailability

85%

Protein binding

9.3%

Metabolism

Mainly hydrolysis to inactive metabolite; CYP450 not appreciably involved

Biological half-life

2 to 3 hours

Excretion

Renal

Identifiers

IUPAC name[show]

CAS Number

·         274901-16-5 

PubChem CID

·         6918537

IUPHAR/BPS

·         6310

DrugBank

·         DB04876 Yes

ChemSpider

·         5293734 Yes

UNII

·         I6B4B2U96P

KEGG

·         D07080 Yes

ChEMBL

·         CHEMBL142703 Yes

ECHA InfoCard

100.158.712 Edit this at Wikidata

Chemical and physical data

Formula

C17H25N3O2

Molar mass

303.399 g/mol

3D model (JSmol)

·         Interactive image

Solubility in water

Freely Soluble in water mg/mL (20 Â°C)

SMILES

InChI

Vildagliptin (previously LAF237, trade names GalvusZomelis,) is an oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin inhibits the inactivation of GLP-1[2][3] and GIP[3] by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucagon release by the alpha cells of the islets of Langerhans in the pancreas.

Vildagliptin has been shown to reduce hyperglycemia in type 2 diabetes mellitus.[2]

Our packaging materials can retain the products' quality and newness even under extreme shipping and handling conditions. Our packaging provides optimum physical protection. We keep the finished assortment of products in highly developed and spacious space. This helps us in keeping products secure and sorted.

Contact Us

311, Atlantis Heights, Sarabhai Main Road, Vadiwadi, Vadodara, Gujarat, 390007, India
Phone :91-265-2313036